Cinnamaldehyde, also known as cinnamic aldehyde, cinnamaldehyde, β-propenal or 3-phenyl-2 acrolein, is an aldehyde organic compound that exists in essential oils such as cinnamon oil, rose oil, and patchouli oil. Its chemical name is triphenylacrolein and its molecular formula is C9H8O. It has a melting point of -8°C and a boiling point of 253°C under normal pressure. It exists in the form of a liquid. Cinnamic aldehyde has two isomers, cis and trans, and natural cinnamaldehyde has a trans structure. Cinnamaldehyde has a strong and long-lasting fragrance of cinnamon oil, has the characteristics of antibacterial, anti-mildew, expansion of blood vessels and lowering blood pressure. It is widely used in the fields of medicine and food industry.
Physiological functions of cinnamaldehyde Cinnamaldehyde has the effect of lowering blood sugar and blood lipid, and can be used to treat type 2 diabetes. Intake of cinnamaldehyde can increase the body's utilization of glucose and esters, and achieve the purpose of lowering blood sugar and blood lipid. Studies have shown that after taking cinnamaldehyde in patients with type 2 diabetes, their fasting blood sugar, triglycerides, and low-density lipoprotein levels are significantly reduced. Cinnamaldehyde can be used for the treatment of cell fibrosis. Studies have shown that cinnamaldehyde can inhibit the proliferation and hypertrophy of renal interstitial fibroblasts and the synthesis and secretion of intercellular collagen caused by high glucose.
The antibacterial effect of cinnamaldehyde. Cinnamaldehyde has a broad-spectrum antibacterial effect. Zhang Wenjuan et al. conducted cinnamaldehyde antifungal experiments on 22 species and 31 strains of conditionally pathogenic fungi. The results showed that cinnamaldehyde has good effects on Aspergillus flavus, Aspergillus fumigatus, Penicillium citrinum and other fungi. Inhibitory effect.
Cinnamaldehyde can increase the active oxygen content in some bacteria, cause oxidative damage to them, and cause their death. Wang Fan et al. used cinnamaldehyde to act on Escherichia coli and Pseudomonas aeruginosa. After treatment with cinnamaldehyde solution, the growth of Escherichia coli was inhibited, and the content of hydrogen peroxide and malondialdehyde in the bacteria increased significantly. There is bacterial membrane on the surface. Although the accumulation of reactive oxygen species has not been detected in its body, its growth and metabolism are also affected.
Metabolism of Cinnamaldehyde. In animal experiments with cinnamon oil, it was found that cinnamaldehyde can be rapidly metabolized into cinnamic acid in rats.