Today, Pharmaceutical Intermediate Supplier will introduce the application of cinnamaldehyde.
Cinnamaldehyde is an aldehyde organic compound. It is a yellow viscous liquid and is found in a large amount in plants such as cinnamon.
Application in medicine
1. Sterilization, disinfection and antisepsis, especially for fungi. For E. coli, Bacillus subtilis and Staphylococcus aureus, Staphylococcus albicans, Shigella dysenteriae, Typhoid and Paratyphoid, Pneumococcus, Aerobacter, Proteus, Anthracnose, Salmonella enteritidis, Vibrio cholerae, etc. Inhibition. And it has a significant bactericidal effect on Gram-positive bacteria, and can be used to treat a variety of diseases caused by bacterial infections. Japanese medical experts have found that cinnamaldehyde has a significant effect on fungi. The antifungal effect of cinnamaldehyde on 22 conditioned pathogenic fungi has shown that cinnamaldehyde is an antifungal active substance, mainly by destroying the fungal cell wall and allowing the drug to penetrate In fungal cells, the organelles are destroyed to play a bactericidal effect.
2. Anti-ulcer, strengthen stomach and intestinal movement. Its mechanism of action is due to the inhibition of ulcer activity factors (gastric fluid and pepsin) and the strengthening of defensive factors (gastric blood flow rate), as well as inhibition of lower gastric mucosal potential and protection of mucosa. In addition, cinnamaldehyde can reduce pancreatic enzyme activity. Cinnamaldehyde is an aromatic gastrostimulant, which has a mild stimulating effect on the stomach and intestines, can promote the secretion of saliva and gastric juice, enhance digestive function, relieve gastrointestinal smooth muscle spasm, and relieve intestinal spasm pain. It is used to treat stomach pain, gastrointestinal flatulence and colic, and has a significant effect of strengthening the stomach and expelling wind.
3. Lipolysis. Cinnamaldehyde has the effect of inhibiting adrenaline and promoting the fat synthesis of glucose. Cinnamic acid also has such effects, but the effect of cinnamaldehyde is much greater than Cinnamic Acid. Therefore, it can be used in blood glucose control drugs to enhance the performance of insulin to replace glucose and prevent diabetes.
4. Antiviral effect. It has strong tumor suppressive effect on influenza virus and SV10 virus.
5. Anti-cancer effect. Can inhibit tumorigenesis, and has anti-mutagenic and anti-radiation effects.
6. Dilate blood vessels and lower blood pressure. It has antihypertensive effect on adrenocortical hypertension.
7. Commonly used in external medicine and synthetic medicine. It is used in massage liquids and beauty products to disperse blood stasis, promote blood circulation, make the skin warm, firm skin tissue, and used externally to massage to relax limbs and body, and improve water retention. It has effects on skin scars, softening and removal of fibroids. It is also used in safflower oil, refreshing oil, active oil and other external medicines. It mainly plays a role in activating collaterals, dispersing blood and congestion. Platelet count. It also has a strong fungicidal effect and suppresses skin fungi. In short, cinnamaldehyde can not only be used as a raw material itself, but also be added to various external medicines and finished medicines. It can also be further processed to synthesize many powerful drugs.
In addition, Cinnamaldehyde, as a hydroxy acid-based fragrance compound, has a good fragrance-holding effect. It is used as a fragrance raw material in perfumery to make the main fragrance more clear. Because it has a higher boiling point than other organic compounds with similar molecular structures, it is often used as a fragrance fixative. Commonly used in soap flavors, to modulate flavors such as gardenia, roses, etc. In food spices, it can be used in apple, cherry, and fruit flavors.